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It is true that some of experiments looked at the distribution of lipid nanoparticles containing an mRNA coding for Luciferase, a protein that exhibits bioluminescence allowing for visualization where the mRNA ended up. Concise review: quantitative detection and modeling the in vivo kinetics of therapeutic mesenchymal stem/stromal cells. 8.7. Guidelines on ensuring the quality and safety of pharmaceuticals and medical devices derived from the processing of autologous human somatic stem cells. PROVES the mRNA moves from the injection site to the blood, then circulates spike proteins throughout the body, attacking the ovaries, liver, neurological tissues, other organs. Disclaimer. You are transferring the vaccine itself, as well as the spike protein, which could result in bleeding and/or blood clots in your child. The biodistribution study of [89 Zr]Zr-DFO-TST001 demonstrated favorable pharmacokinetics with a relatively long half-life in vivo (Fig. This not only leads to impaired MAVS [mitochondrial antiviral signaling] response but also aggravates inflammation and cell death.. Manipulation of mitochondria by virus may lead to mitochondrial dysfunction and increased oxidative stress ultimately leading to loss of mitochondrial integrity and cell death , Mitochondrial fission enables removal of the damaged portion of a mitochondrion to be cleared by mitophagy (a special form of autophagy). After spending 20 hours of research, I found there are no animal biodistribution studies of mRNA vaccines done by Pfizer, Moderna, or J and J published on an internet search. Biodistribution. Whats more, because the RNA code has been enriched with extra guanines (Gs) and cytosines (Cs), and configured as if its a human messenger RNA molecule ready to make protein by adding a polyA tail, the spike proteins RNA sequence in the vaccine looks as if it is part bacteria,17 part human18 and part viral at the same time. What does this startling discovery mean for blood donations? Find the original research and move on! SARS-CoV-2 MRNA Vaccine (BNT162, PF-07302048) 2.6.4 Summary of Pharmacokinetic Study. Read our disclaimer for details. SARS-CoV-2 MRNA Vaccine (BNT162, PF-0 7302048)2.6.4 . However, while the spike protein found in the virus is bad, the spike protein your body produces in response to the vaccine is far worse. Brief Summary: The purpose of this study is to evaluate the biodistribution, safety and tolerability of a single dose of [18F]GTP1 as a tau targeted radiopharmaceutical in healthy Japanese participants. A biodistribution study was conducted using ddY mice (male, 5 weeks old). Bittorf P, Bergmann T, Merlin S, Olgasi C, Pullig O, Sanzenbacher R, Zierau M, Walles H, Follenzi A, Braspenning J. Mol Ther Methods Clin Dev. The EIN for the organization is 59-1630423. Tags:Japan Pfizer spike proteins vaccines. 2 Research, Takeda Pharmaceutical Company Limited, 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa, Japan. DNA Extraction Method Affects the Detection of a Fungal Pathogen in Formalin-Fixed Specimens Using qPCR. We thought the spike protein was a great target antigen; we never knew the spike protein itself was a toxin and was a pathogenic protein. Change), You are commenting using your Twitter account. When that happens, it can cause platelets to clump together, resulting in blood clots, and/or cause abnormal bleeding, Pfizer documents submitted to the European Medicines Agency also show the company failed to follow industry-standard quality management practices during preclinical toxicology studies and that key studies did not meet good laboratory practice standards. Specific alterations make it far more toxic than that found on the virus itself. No, the Japanese biodistribution study shows nothing of the sort. "Biodistribution" study of mRNA vaccines. Here in fact he spells out that the Japanese Pfizer biodistribution studies have found a high concentration of the Lipid Nanoparticles in the ovaries--a known result to Pfizer and the FDA . Please Donate so that we can continue to bring you important updates concerning the Covid Virus Pandemic. Image . Canadian vaccine expert Dr. Byram Bridle recently spoke of the terrifying reasons serious side effects, including heart inflammation and vaccine-induced immune thrombotic thrombocytopenia (VITT), may occur in those who have received the COVID-19 vaccine. I wanted links for my wife who is Japanese and could not understand my resistance to them. Is there a translated version to English of the study somewhere we can access? Youll also want to make sure your vitamin D level is optimized to between 60 ng/mL and 80 ng/mL (100 nmol/L to 150 nmol/L), ideally through sensible sun exposure. DO NOT forget Japanese biodistribution study looking at lipid nano-particles in rats & how they bio-accumulated in first 48 hours post administration; understand that this links direct to COVID jabs Dr. Byram Bridle was attacked for his work showing that content of the COVID VACCINE did not stay in the injection site (arm) but leeched into the . I thought this would be an easy blog to write, cut and dry. What did the initial Pfizer biodistribution studies show? But, as you can see below, unlike Bridle, Politifact neglected to go beyond interviewing someone with such a huge stake in the vaccines success. Once it gets in the blood, it accumulates in a number of tissues such as the spleen, the bone marrow, the liver, the adrenal glands. The current study investigated SARS-CoV-2 viral load, biodistribution and anti-SARS-CoV-2 antibody formation in patients suffering from severe corona virus disease 2019 (COVID-19) induced acute respiratory distress syndrome (ARDS). We do not have all the animal or clinical data needed to completely evaluate long term safety of the mRNA vaccines. In the biodistribution study, luciferase RNA-encapsulated LNP was administered intramuscularly to BALB/c mice, and the expression of luciferase was observed at the site of administration, and also in the liver, although at a lower level. -. The study is titled, "Placebo-controlled randomized double-blind (evaluators, patients) multi-facility joint parallel-group comparison . The research,4,5 previously unseen, demonstrates a huge problem with all COVID-19 vaccines. Japanese Biodistribution study that Dr. Byram Bridle warned about showing that lipid-nano particles, the mRNA & thus possible spike bio-accumulated in distant tissue & organs based on rat model; Table Bridle was pilloried by all, the media, his insane putrid University colleagues etc. Theres also evidence suggesting the SARS-CoV-2 spike protein may be a prion, which is yet another piece of really bad news, particularly as it pertains to vaccine-induced spike protein. . https://www.regulations.gov/docket/FDA-2021-P-0521/document. eCollection 2020 Sep 11. You can also boost your sulfate by taking Epsom salt baths. 8600 Rockville Pike 8.6. Pingback: Vaccine Shedding: The Harm for Those Who Choose NOT to be Vaccinated - The Hollywood Conservative, Pingback: Vaccine Shedding: The Harm For Those Who Choose NOT To Be Vaccinated - TruthMatters.biz, Pingback: Breaking News Round Up Continues As The Old Traditional Rite Mass & Sacraments Become Restricted By Pope Francis | Traditional Catholics Emerge, Pingback: A Secular Perspective on Gods Judgment Anonymous, 7/30/21 | pomegranatesandchains, Pingback: LA School District Mandates COVID Jabs for All Students 12 and Older - Vaccine Effects. (a) Number of cell-based therapeutic product in cell formulation and number of cell-based therapeutic product with or without biodistribution study in (b) cell-suspension CTP and (c) tissue or cell-sheet CTP (refer to Supplementary Table1). The research, previously unseen, demonstrates a huge problem with all COVID-19 vaccines, The assumption that vaccine developers have been working with is that the mRNA in the vaccines would primarily remain in and around the vaccination site. 2021 The Japanese Society for Regenerative Medicine. As we reported last June 14, Bridle received a copy of a Japanese biodistribution study, which had been withheld from the public, as a result of a freedom of information request made to the Japanese government for data from Pfizer. Why? Thus, a low ACE2 activity subsequent to SARS-CoV-2 infection leads to imbalance in renin-angiotensin system with relative excess of angiotensin II. It was a pre-clinical biodistribution study. A biodistribution study of the Pfizer Covid-19 injection suggests a suspension of the use of mRNA 'Vaccines' is urgently required and blood donor organisations need to take a long hard look at their policies surrounding the acceptance of donations of blood from people who have received an mRNA based Covid-19 injection. I had the same link as you but now it is not active. Biomedicines. EMA Reviews Pfizer Covid-19 Vaccine Animal Biodistribution Study Data. Thus, there is accumulation of damaged and dysfunctional mitochondria. Since any protein in the blood will concentrate in breast milk, observing that the spike protein gets into circulation is even more disturbing. In this work, we have confirmed results in the literature and . Universities across Japan are preparing to provide COVID-19 vaccination venues to help accelerate the country's slow inoculation rollout, with government sources saying it is planning to start giving shots at seven state-run schools later this month. government site. Arthritis Care Res (Hoboken). Production and hosting by Elsevier B.V. All authors declare that they have no competing interests. 2015;99(23):99079922. To conduct BD studies, it is necessary to understand regulatory requirements, implementation status, and analytical methods. Because the synthetic mRNA in the vaccine has been programmed to instruct your cells to produce an unnatural, genetically engineered spike protein. Apart from its role in energy production, mitochondria are crucial for innate immunity, reactive oxygen species (ROS) generation, and apoptosis; all of these are important in COVID-19 pathogenesis. In my interview with Seneff and Mikovits (see earlier hyperlink), they both stressed that the key danger both in COVID-19 and with the vaccines is the spike protein itself. sharing sensitive information, make sure youre on a federal Information about the cons of the vaccines is very difficult to find. And of particular concern for me is it accumulates in the ovaries, in quite high concentrations.. Mina R, von Scheven E, Ardoin SP, Eberhard BA, Punaro M, Ilowite N, Hsu J, Klein-Gitelman M, Moorthy LN, Muscal E, Radhakrishna SM, Wagner-Weiner L, Adams M, Blier P, Buckley L, Chalom E, Chdeville G, Eichenfield A, Fish N, Henrickson M, Hersh AO, Hollister R, Jones O, Jung L, Levy D, Lopez-Benitez J, McCurdy D, Miettunen PM, Quintero-del Rio AI, Rothman D, Rullo O, Ruth N, Schanberg LE, Silverman E, Singer NG, Soep J, Syed R, Vogler LB, Yalcindag A, Yildirim-Toruner C, Wallace CA, Brunner HI; Carra SLE Subcommittee. It is necessary to understand their biodistribution. When in circulation, the spike protein can bind to the receptors that are on our platelets and the cells that line our blood vessels. In the case of the Pfizer COVID mRNA vaccine, these newly revealed documents raise additional questions about both the genotoxicity and reproductive toxicity risks of this product. Princess Bajrakitiyabha of Thailand collapses, Vaxxed and unvaxxed coming down with same ailments, Sasha Latypova reveals COVID law and contracts, Todd Callender explains the legal framework for pandemics, Sasha Latypova gives a speech in Stockholm, Centers for Disease Control and Prevention, Fact Sheet for Healthcare Providers Administering Vaccine, https://www.fda.gov/media/144413/download, https://uncoverdc.com/wp-content/uploads/2021/05/Bridle.pdf.pagespeed.ce.aKOeaMY9Wh.pdf, https://omny.fm/shows/on-point-with-alex-pierson/new-peer-reviewed-study-on-covid-19-vaccines-sugge, https://www.lifesitenews.com/news/vaccine-researcher-admits-big-mistake-says-spike-protein-is-dangerous-toxin/, https://trialsitenews.com/did-pfizer-fail-to-perform-industry-standard-animal-testing-prior-to-initiation-of-mrna-clinical-trials/, https://www.youtube.com/watch?v=Du2wm5nhTXY, https://www.bitchute.com/video/UfFOTCxRORsp/, https://www.bitchute.com/video/T71ZVNAXi0jW/, https://rumble.com/v15oqc7-dr.-richard-urso-the-explosion-of-cancer-and-latent-disease-from-the-vaccin.html, First case of autopsy in a patient vaccinated against COVID-19, Report: mRNA vaccines is converted to DNA in the liver, Vaccine-Induced Covid-19 Mimicry Syndrome, Brian Gerrish explains the psychological manipulation of the public . Consistent data shows the virus is less severe than influenza in children, strengthening the argument of do kids need the vaccine? Voicing his concern, Bridle asserts: Thats not how this is supposed to work; our kids should not be the guinea pigs. So the Japanese medicines regulator had required Pfizer to do a study where they looked at how the vaccine distributed around the body, in this case of a . Stem Cells Transl Med. The mean concentrations and tissue distribution pattern were broadly similar between the sexes. Spike Protein Is Very Dangerous, Its Cytotoxic (Robert Malone, Steve Kirsch, Bret Weinstein). All of this also suggests that for individuals who are at low risk for COVID-19, children and teens in particular, the risks of these vaccines far outweigh the benefits. The research, previously unseen, demonstrates a huge problem with all COVID-19 vaccines. At first glance, this information seems relatively straightforward. The bottom line is mRNA Covid vaccines are still considered experimental by the FDA as research continues to be done. Canadian immunologist and vaccine researcher Byram Bridle, Ph.D., has gained access to Pfizer's biodistribution study from the Japanese regulatory agency. When the spike protein interacts with the ACE2 receptor, it can disrupt mitochondrial signaling, thereby inducing the production of reactive oxygen species and oxidative stress. This document . Clipboard, Search History, and several other advanced features are temporarily unavailable. Our democracy no longer represents the people. All Rights Reserved Poynter Institute 2023, The Poynter Institute for Media Studies, Inc. is a non-profit 501(c)3. This assumption was wrong. -, Brooks A., Futrega K., Liang X., Hu X., Liu X., Crawford D.H.G. After the protein piece is made, the cell breaks down the instructions and gets rid of them. When that happens, it can do one of two things: it can either cause platelets to clump, and that can lead to clottingthats exactly why weve been seeing clotting disorders associated with these vaccines. As part of that research, he and a team of international scientists requested a Freedom of Information Act (FOIA) access to Pfizer's biodistribution study from the Japanese regulatory agency. If you would like to help raise awareness of the facts surrounding children and COVID19 vaccines, please share. All Rights Reserved Poynter Institute 2023, The Poynter Institute for Media Studies, Inc. is a non-profit 501(c)3. In fragile patients receiving the blood, the damage could be lethal. The greatest mean concentration was found remaining in the injection site at each time point in both sexes. The research,4,5 previously unseen, demonstrates a huge problem with all COVID-19 vaccines. its important. 8.8. I am giving you the technical version so you can see for yourself the actual data reviewed by EMA. Biodistribution (BD) analysis is performed to determine the distribution and the persistence of the vector/virus to target and nontarget tissues following direct in vivo administration in animals. It is certainly understandable why the vaccine was rushed into use as an experimental product under emergency use authority, but these new findings suggest that routine quality testing issues were overlooked in the rush to authorize use. Playing Hardball in Government and Politics, Nuclear War At the Abyss of Mass Extermination, Pfizer Bio-Distribution Study Submitted to the Japanese Government, Canadian immunologist and vaccine researcher Byram Bridle, Ph.D., has gained access to Pfizers biodistribution study from the Japanese regulatory agency. Documents obtained from Japanese regulatory agency reveal that Pfizer biodistribution studies showed that mRNA and spike proteins circulate widely throughout the body. Japan shares biodistribution study of Pfizer COVID-19 vaccine May 27, 2021 Tags: Japan Pfizer spike proteins vaccines The designers of the COVID-19 vaccines expected the contents of a jab to remain in the muscular tissue where they were injected, usually an arm. Elaborating on the implications of these findings, he remarked: We have known for a long time that the spike protein is a pathogenic protein. New Peer Reviewed Study on COVID-19 Vaccines Suggests Why Heart Inflammation, Blood Clots and Other Dangerous Side Effects Occur. The biodistribution study obtained by Bridle showed lipid nanoparticles from the vaccine did not stay in the deltoid muscle where they were injected as the vaccine's developers claimed would happen, but circulated throughout the body and accumulated in large concentrations in organs and tissues, including the spleen, bone marrow, liver, adrenal Pingback: Lying to children - Change is Always Possible. Current Red Cross guidelines state, In most cases, theres no deferral time if you receive a vaccine, a protocol which doesnt sit well with Bridle, who remarked, We dont want [a] transfer of these pathogenic spike proteins to fragile patients who might need a blood transfusion. 1. Some of the protein will go to the local draining lymph node in order to activate the immune system., Please consider leaving a comment on the FDA petition to revoke the EUA & prevent licensure of the COVID injections. No evidence of vaccine-related macroscopic or microscopic findings were found in the ovaries in the repeat-dose toxicity studies (Study 38166 and Study 20GR142), were identified in the DART, Developmental and Reproductive Toxicology, study.*, The bottom line is mRNA Covid vaccines are still considered experimental by the FDA as. So, by vaccinating people we are inadvertently inoculating them with a toxin.. Spike protein does not attack anything, it only aims to activate the immune response, it is not the same as coronavirus spike protein and after vaccination, it is created in a dose 100 thousand times lower than in viral infection. I want to pass it on to some doctors in Japan who have no idea about its existence. Support responsible news and fact-based information today! Using Luciferine to follow biodistribution of a product is common practice. Accessibility This is about as diabolical as it gets. To combat the toxicity of the spike protein, youll want to optimize autophagy, which may help digest and remove the spike proteins. Luciferase signals at the injection sites, most likely reflecting distribution to the lymph nodes draining the injection sites, peaked 6h post injection with signals of approximately 10 000 times of buffer control animals. Remember, the research cited by Bridle at the beginning of this article found the spike protein accumulates in the spleen, among other places. Multifunctional NP-based technologies with diagnostic and therapeutic functions are being developed for in vivo applications. "The results of this leaked Pfizer study tracing the biodistribution of the vaccine mRNA are not surprising, but the implications are terrifying," Stephanie Seneff, a senior research scientist. Methods: This is a retrospective single-center study in 23 patients with COVID-19-induced ARDS. in Japan for DNA vaccines and recombinant virus vaccines, or prior to the initiation of a large-scale clinical trial in Japan for LNP-mRNA vaccines. Family threatened, his life threatened. Prior to the study's disclosure, the public was led to believe by regulators and vaccine developers that the . Stephanie Seneff, Ph.D., and Judy Mikovits, Ph.D. The mRNA enters your bloodstream and accumulates in a variety of organs, primarily your spleen, bone marrow, liver, adrenal glands and, in women, the ovaries. Blood clots are a common result, and can occur either because the platelets clump together in response to the vessel wall damage, or because your anticlotting mechanism has been compromised. Thrombocytopenia is a commonly-reported side effect of COVID-19 vaccines, as are blood clots, strokes and lethal heart attacks all of which are pointing toward spike proteins causing vascular damage. Remember to check the date when the fact-check you are reading was published before sharing it. Shedding is the dissemination of the viral vectors (e.g. An official website of the United States government. The designers of the COVID-19 vaccines expected the contents of a jab to remain in the muscular tissue where they were injected, usually an arm. This assumption was wrong. A study document obtained from the Japanese regulatory agency shows that the vaccine contents enter the bloodstream and travel to the various organs.Lab animals injected with purified spike protein into their bloodstream developed cardiovascular problems, and the spike protein was also demonstrated to cross the blood brain barrier and cause damage to the brain. As a public-health body safeguarding medicines in the European Union (EU), EMA only recommends approval of a vaccine for COVID-19 after a thorough evaluation demonstrating the same high . A study with the same platform vector ChAdOx -1 (hepatitis B virus) and two studies with a similar viral vector (ChAd63) were also carried out and the results are summarised qualitatively in the EPAR. HHS Vulnerability Disclosure, Help This is a nonprofit education and research site. Nothing whatsoever on this site is monetized, not even the Amazon links. I therefore claim fair use of materials featured here. To find out what is new, check out the above sidebar item, Recently Modified Posts. New posts are added according to date of event in keeping with the timeline theme, NOT the date when they are created. Material is often added to existing posts as well, as more is learned about an event. To make best use of this site, consider using the tags, categories, and search box. Many posts also have a See also, on this site list. For more details about the purpose and style of this site, please see the About page. The biodistribution of hybrid nanostructures is a major subject of current nanomedical research. Women have reported changes in menstruation after taking mRNA vaccines. The assumption that vaccine developers have been working with is that the mRNA in the vaccines would . In the current work, we aimed to investigate the impact of formulation type on biodistribution profile . Instead it stays open and remains attached to the ACE2 receptor, thereby disabling it and causing a host of problems that lead to heart, lung and immune impairment. Before It is a toxin. A biodistribution study of the Pfizer Covid-19 injection suggests a suspension of the use of mRNA 'Vaccines' is urgently required and blood donor organisations need to take a long hard look at their policies surrounding the acceptance of donations of blood from people who have received an mRNA based Covid-19 injection. The first section is labeled: SARS-CoV-2 mRNA Vaccine (BNT162, PF-07302048) 2.6.4 Summary of pharmacokinetic study Bridle explains the study absolutely refutes the premise that the COVID-19 vaccine stays in the shoulder muscle, asserting: The short answeris absolutely not. https://www.ema.europa.eu/en/documents/assessment-report/comirnaty-epar-public-assessment-report_en.pdf. The Japanese biodistribution study results are consistent with Pfizer's that was submitted to the European Medicines Agency (EMA) in February 2021. Methods This is a . The biodistribution was also studied in rats using radiolabeled LNP and luciferase modRNA (study 185350).. Interestingly, we recently carried our similar study of safety and biodistribution of laser-synthesized Si nanoparticles 56,74, which present another promising material for imaging and therapy . Very often, the damage is caused by the immune system going on the attack, damaging blood vessel walls, and removing several of the anti-clotting mechanisms. The end result can be lethal, and this chain of events is exactly what these COVID-19 vaccines are setting into motion. Biodistribution; Cell therapy product; Imaging; MRI; PET; SPECT; qPCR. Its past time to #RevoketheEUA https://t.co/ZdeHCKXyPb, BREAKING: Dr. Byram Bridle sent me his report: 'Why Parents, Teens, and Children Should Question the COVID-19 Vaccine'He's an Associate Professor of Viral Immunology at the University of Guelph who brought attention to the Pfizer Japanese study. Some people, this gets into circulation, and when that happens, in some people, they can cause damage, especially to the cardiovascular system., https://uncoverdc.com/2021/05/31/vaccine-expert-warns-we-made-a-big-mistake/, In paragraph 3 you quote him as saying inter alia, regarding the spike protein that We thought the spike protein was a great target antigen; we never knew it was a toxin. However, para 8 he states We have known for a long time that the spike protein is a pathogenic protein. Bridle also cites recent research showing the spike protein remained in the bloodstream of humans for 29 days. Assuming that the spike protein would not enter into the circulatory system was a grave mistake, according to Bridle, who calls the Japanese data clear-cut evidence that the vaccine, and the spike protein produced by it, enters your bloodstream and accumulates in vital organs. . This is important to understand. In short, when you get the COVID-19 vaccine, you are being injected with an agent that instructs your body to produce the bioweapon in its own cells. Canadian immunologist and vaccine researcher Byram Bridle, Ph.D., has gained access to Pfizer's biodistribution study from the Japanese regulatory agency. The short answer is: absolutely not. What is the length of time the vaccine exists in the body after vaccination? In 2020, Bridle was awarded a $230,000 government grant for research on COVID vaccine development. Listing a study does not mean it has been evaluated by the U.S. Federal Government. The site is secure. This information is found on the internet leading us to assume, yes, biodistribution studies in animals were conducted by Pfizer. The accumulation in the ovaries is shown on the second page. Whats more, TrialSite News reports6 that Pfizer documents submitted to the European Medicines Agency [EMA] reveal the company did not follow industry-standard quality management practices during preclinical toxicology studies as key studies did not meet good laboratory practice (GLP)., Neither reproductive toxicity nor genotoxicity (DNA mutation) studies were performed, both of which are considered critical when developing a new drug or vaccine for human use. And, since the spike protein doesnt enter into the membrane of the cell, theres a high risk that it can become problematic if indeed it works like a prion. About page a translated version to English of the sort the greatest mean concentration was found remaining the... On biodistribution profile quality and safety of pharmaceuticals and medical devices derived from the processing autologous. The sort Liang X., Crawford D.H.G study shows nothing of the vaccines! 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Specimens using qPCR experimental by the FDA as and several other advanced features are temporarily unavailable translated to..., 5 weeks old ) work ; our kids should not be the pigs., Japan genetically engineered spike protein is a major subject of current nanomedical research both sexes PET SPECT... A federal information about the purpose and style of this site, please see the about page facts... To investigate the impact of formulation type on biodistribution profile less severe than influenza in children, biodistribution study japan the of! Is monetized, not even the Amazon links tags, categories, and Judy,. End result can be lethal, and Judy Mikovits, Ph.D diagnostic and therapeutic functions being! The toxicity of the study & # x27 ; s disclosure, the Poynter Institute,... Futrega K., Liang X., Crawford D.H.G: this is about as diabolical as it gets vaccine. Was awarded a $ 230,000 government grant for research on Covid vaccine development animal or clinical data needed to evaluate...

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biodistribution study japan

biodistribution study japan

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biodistribution study japan